Background Neurocognitive deficits exist in euthymic patientswith bipolar disorder, but relationships between symptoms, psychosocial andneurological factors remainuncertain. Aims Tomeasure neurocognitive function in bipolardisorder and explore links to sub-syndromalmood symptoms, soft neurological signs andpsychosocial
نویسندگان
چکیده
Results Performances ontests reflecting executive function andverbal memory (butnot attention) were significantlypoorer inthe bipolardisorder group.Sub-syndromalmood symptoms produced small cognitive effects, predominantlyonverbalmemory.Soft neurological signs, especially frontal signs, weremarked; somepatients showed marked social disability which correlated strongly with soft neurological signs but weakly with executive dysfunction, which was linked to illness episodes.
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